Cargando…
Directed evolution of prenylated FMN-dependent Fdc supports efficient in vivo isobutene production
Isobutene is a high value gaseous alkene used as fuel additive and a chemical building block. As an alternative to fossil fuel derived isobutene, we here develop a modified mevalonate pathway for the production of isobutene from glucose in vivo. The final step in the pathway consists of the decarbox...
Autores principales: | Saaret, Annica, Villiers, Benoît, Stricher, François, Anissimova, Macha, Cadillon, Mélodie, Spiess, Reynard, Hay, Sam, Leys, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421414/ https://www.ncbi.nlm.nih.gov/pubmed/34489427 http://dx.doi.org/10.1038/s41467-021-25598-0 |
Ejemplares similares
-
The role of conserved residues in Fdc decarboxylase in prenylated flavin mononucleotide oxidative maturation, cofactor isomerization, and catalysis
por: Bailey, Samuel S., et al.
Publicado: (2018) -
Enzymatic control of cycloadduct conformation ensures reversible 1,3 dipolar cycloaddition in a prFMN dependent decarboxylase
por: Bailey, Samuel S., et al.
Publicado: (2019) -
Structure and Mechanism of Pseudomonas aeruginosa PA0254/HudA, a prFMN-Dependent Pyrrole-2-carboxylic Acid Decarboxylase
Linked to Virulence
por: Payne, Karl A. P., et al.
Publicado: (2021) -
Fermentative production of isobutene
por: van Leeuwen, Bianca N. M., et al.
Publicado: (2012) -
Toolbox for the structure-guided evolution of ferulic acid decarboxylase (FDC)
por: Duță, Horia, et al.
Publicado: (2022)