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An alcoholic extract of Thuja orientalis L. leaves inhibits autophagy by specifically targeting pro-autophagy PIK3C3/VPS34 complex

Autophagy is a lysosome-dependent degradation program to maintain cellular homeostasis in response to a variety of stressful conditions, such as long-lived or non-functional subcellular organelles, protein aggregates, nutrient limitation, and virus/bacteria infection. Accordingly, dysregulation of a...

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Detalles Bibliográficos
Autores principales: Jung, Juneyoung, Chun, Yoomi, Jang, Young Pyo, Oh, Myung Sook, Kim, Jeong Hee, Kim, Joungmok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421415/
https://www.ncbi.nlm.nih.gov/pubmed/34489486
http://dx.doi.org/10.1038/s41598-021-97216-4