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Growth-coupled selection of synthetic modules to accelerate cell factory development

Synthetic biology has brought about a conceptual shift in our ability to redesign microbial metabolic networks. Combining metabolic pathway-modularization with growth-coupled selection schemes is a powerful tool that enables deep rewiring of the cell factories’ biochemistry for rational bioproductio...

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Detalles Bibliográficos
Autores principales: Orsi, Enrico, Claassens, Nico J., Nikel, Pablo I., Lindner, Steffen N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421431/
https://www.ncbi.nlm.nih.gov/pubmed/34489458
http://dx.doi.org/10.1038/s41467-021-25665-6