Template activating factor-I epigenetically regulates the TERT transcription in human cancer cells

Telomere, the terminus of linear chromosome in eukaryotes, is composed of specific repeat DNA which is mainly synthesized by a protein complex called telomerase. The maintenance of telomere DNA is important for unlimited proliferative capacity of cancer cells. The telomerase activity is controlled b...

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Detalles Bibliográficos
Autores principales: Kato, Kohsuke, Kawaguchi, Atsushi, Nagata, Kyosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421516/
https://www.ncbi.nlm.nih.gov/pubmed/34489496
http://dx.doi.org/10.1038/s41598-021-97009-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421516/
https://www.ncbi.nlm.nih.gov/pubmed/34489496
http://dx.doi.org/10.1038/s41598-021-97009-9

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