A Kinetic Response Model for Standardized Regression Analyses of Inflammation-Triggered Hypothermic Body Temperature-Time Courses in Mice

LPS is frequently used to induce experimental endotoxic shock, representing a standard model of acute inflammation in mice. The resulting inflammatory response leads to hypothermia of the experimental animals, which in turn can be used as surrogate for the severity of systemic inflammation. Although...

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Detalles Bibliográficos
Autores principales: Diebner, Hans H., Reinke, Sören, Rösen-Wolff, Angela, Winkler, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421519/
https://www.ncbi.nlm.nih.gov/pubmed/34504434
http://dx.doi.org/10.3389/fphys.2021.634510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421519/
https://www.ncbi.nlm.nih.gov/pubmed/34504434
http://dx.doi.org/10.3389/fphys.2021.634510

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