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SMPDL3B Predicts Poor Prognosis and Contributes to Development of Acute Myeloid Leukemia

Background: Acute myeloid leukemia (AML), characterized by the low cure rate and high relapse, urgently needs novel diagnostic or prognostic biomarkers and potential therapeutic targets. Sphingomyelin Phosphodiesterase Acid Like 3B (SMPDL3B) is a negative regulator of Toll-like receptor signaling th...

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Detalles Bibliográficos
Autores principales: Qu, Huiqing, Zhu, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421532/
https://www.ncbi.nlm.nih.gov/pubmed/34504869
http://dx.doi.org/10.3389/fmolb.2021.695601