Assessment of E. coli Expression System for Overexpression of Active Recombinant Ocriplasmin

Purpose: Ocriplasmin (Jetrea TM) is a FDA approved recombinant enzyme utilized in the treatment of vitreomacular adhesion (VMA). This is a recombinant C-terminal fragment of human plasmin produced using yeast Pichia pastoris. Since ocriplasmin does not contain any Oor N-glycosylation or some other p...

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Detalles Bibliográficos
Autores principales: Baghban, Roghayyeh, Farajnia, Safar, Ghasemi, Younes, Mortazavi, Mojtaba, Samadi, Naser, Zarghami, Nosratollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421613/
https://www.ncbi.nlm.nih.gov/pubmed/34513632
http://dx.doi.org/10.34172/apb.2021.065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421613/
https://www.ncbi.nlm.nih.gov/pubmed/34513632
http://dx.doi.org/10.34172/apb.2021.065

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