Cargando…

Assessment of E. coli Expression System for Overexpression of Active Recombinant Ocriplasmin

Purpose: Ocriplasmin (Jetrea TM) is a FDA approved recombinant enzyme utilized in the treatment of vitreomacular adhesion (VMA). This is a recombinant C-terminal fragment of human plasmin produced using yeast Pichia pastoris. Since ocriplasmin does not contain any Oor N-glycosylation or some other p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baghban, Roghayyeh, Farajnia, Safar, Ghasemi, Younes, Mortazavi, Mojtaba, Samadi, Naser, Zarghami, Nosratollah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Tabriz University of Medical Sciences 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421613/ https://www.ncbi.nlm.nih.gov/pubmed/34513632 http://dx.doi.org/10.34172/apb.2021.065

Ejemplares similares

Engineering of Ocriplasmin Variants by Bioinformatics Methods for the Reduction of Proteolytic and Autolytic Activities
por: Baghban, Roghayyeh, et al.
Publicado: (2021)

Mutational Analysis of Ocriplasmin to Reduce Proteolytic and Autolytic Activity in Pichia pastoris
por: Baghban, Roghayyeh, et al.
Publicado: (2020)

Multiplex Genome Editing in Chinese Hamster Ovary Cell Line Using All-in-One and HITI CRISPR Technology
por: Safari, Fatemeh, et al.
Publicado: (2021)

Expression and Evaluation of HuscFv Antibody -PE40 Immunotoxin for Target Therapy of EGFR-Overexpressing Cancers
por: Falahatgar, Dianoush, et al.
Publicado: (2018)

Optimized Signal Peptide for Secretory Expression of Human Recombinant Somatropin in E. coli
por: Ahmadi, Zeynab, et al.
Publicado: (2023)

Association of rs780094 polymorphism of glucokinase regulatory protein with non-alcoholic fatty liver disease
por: Mohammadi, Saba, et al.
Publicado: (2020)

Current trends in targeted therapy for drug-resistant infections
por: Rahbarnia, Leila, et al.
Publicado: (2019)

Ocriplasmin for Vitreoretinal Diseases
por: Tsui, Irena, et al.
Publicado: (2012)

Ocriplasmin: who is the best candidate?
por: Prospero Ponce, Claudia M, et al.
Publicado: (2016)

An update of the recombinant protein expression systems of Cyanovirin-N and challenges of preclinical development
por: Lotfi, Hajie, et al.
Publicado: (2018)

Retinal breaks due to intravitreal ocriplasmin
por: Silva, Ruwan A, et al.
Publicado: (2014)

Ocriplasmin for Treatment of Vitreomacular Traction: An Update
por: Khan, Mohammed Ali, et al.
Publicado: (2016)

Assessment of Ocriplasmin Effects on the Vitreoretinal Compartment in Porcine and Human Model Systems
por: Jonckx, Bart, et al.
Publicado: (2017)

Rhegmatogenous retinal detachment following intravitreal ocriplasmin
por: Madi, Haifa A., et al.
Publicado: (2016)

Italian real-life experience on the use of ocriplasmin
por: Barca, Francesco, et al.
Publicado: (2018)

Evaluation of Recombinant Human Growth Hormone Secretion in E. coli using the L-asparaginase II Signal Peptide
por: Zamani, Mozhdeh, et al.
Publicado: (2016)

In-vitro Effect of Imipenem, Fosfomycin, Colistin, and Gentamicin Combination against Carbapenem-resistant and Biofilm-forming Pseudomonas aeruginosa Isolated from Burn Patients
por: Memar, Mohammad Yousef, et al.
Publicado: (2021)

Functional improvement assessed by multifocal electroretinogram after Ocriplasmin treatment for vitreomacular traction
por: Rossi, Settimio, et al.
Publicado: (2016)

Vitreomacular traction quantitative cutoffs for the assessment of resolution after ocriplasmin intravitreal treatment
por: Arrigo, Alessandro, et al.
Publicado: (2020)

Macular Hole Progression following Ocriplasmin Intravitreal Injection
por: Casswell, Edward, et al.
Publicado: (2014)

Incomplete Vitreomacular Traction Release Using Intravitreal Ocriplasmin
por: Chin, Eric K., et al.
Publicado: (2014)

Profile of ocriplasmin and its potential in the treatment of vitreomacular adhesion
por: Stefanini, Francisco R, et al.
Publicado: (2014)

Myopic macular hole detachment associated with intravitreal ocriplasmin
por: Goh, Li Yen, et al.
Publicado: (2020)

OCRIPLASMIN FOR VITREOMACULAR TRACTION IN CLINICAL PRACTICE: The INJECT Study
por: Steel, David H. W., et al.
Publicado: (2020)

The Challenges of Recombinant Endostatin in Clinical Application: Focus on the Different Expression Systems and Molecular Bioengineering
por: Mohajeri, Abbas, et al.
Publicado: (2017)

Cytoplasmic Chaperones Enhance Soluble Expression of Anti-EGFR huscFv in Escherichia coli
por: Nazari, Atefeh, et al.
Publicado: (2020)

Effect of Culture Condition Variables on Human Endostatin Gene Expression in Escherichia coli Using Response Surface Methodology
por: Mohajeri, Abbas, et al.
Publicado: (2016)

Ocriplasmin use in a selected case with preserved visual acuity
por: Rossi, Settimio, et al.
Publicado: (2015)

Cost-effectiveness of ocriplasmin for the treatment of vitreomacular traction and macular hole
por: Bennison, Craig, et al.
Publicado: (2016)

RGD delivery of truncated coagulase to tumor vasculature affords local thrombotic activity to induce infarction of tumors in mice
por: Jahanban-Esfahlan, Rana, et al.
Publicado: (2017)

Adipocyte Derived Hormones Gene Expression, Resistin and Visfatin, in AGS Gastric Cancer Cell Line
por: Gorgian Mohammadi, Masumeh, et al.
Publicado: (2013)

Phenotypic and genotypic characterization of Escherichia Coli O111 serotypes
por: Alikhani, Mohammad Yousef, et al.
Publicado: (2011)

Ocriplasmin for symptomatic vitreomacular adhesion: an evidence-based review of its potential
por: Song, Su Jeong, et al.
Publicado: (2014)

Release of experimental retinal vein occlusions by direct intraluminal injection of ocriplasmin
por: de Smet, Marc D, et al.
Publicado: (2016)

Visual function response to ocriplasmin for the treatment of vitreomacular traction and macular hole
por: Jackson, Timothy L., et al.
Publicado: (2017)

Floaters and reduced contrast sensitivity after successful pharmacologic vitreolysis with ocriplasmin
por: Khoshnevis, Matin, et al.
Publicado: (2016)

Multimodal imaging of macular subretinal deposits following intravitreal ocriplasmin injection
por: Chow, Nicholas, et al.
Publicado: (2018)

THE OASIS MP-1 SUBSTUDY: Characterization of the Effect of Ocriplasmin on Microperimetry Parameters
por: Sadda, SriniVas R., et al.
Publicado: (2019)

Effects of Chrysin-PLGA-PEG Nanoparticles on Proliferation and Gene Expression of miRNAs in Gastric Cancer Cell Line
por: Mohammadian, Farideh, et al.
Publicado: (2016)

Prevalence and antibiotic resistance patterns of diarrheagenic Escherichia coli isolated from adolescents and adults in Hamedan, Western Iran
por: Alikhani, Mohammad Yousef, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_3fttm27jesp1616upek5itld4s