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A Multi-Omics Approach Using a Mouse Model of Cardiac Malformations for Prioritization of Human Congenital Heart Disease Contributing Genes

Congenital heart disease (CHD) is the most common type of birth defect, affecting ~1% of all live births. Malformations of the cardiac outflow tract (OFT) account for ~30% of all CHD and include a range of CHDs from bicuspid aortic valve (BAV) to tetralogy of Fallot (TOF). We hypothesized that trans...

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Detalles Bibliográficos
Autores principales: Matos-Nieves, Adrianna, Manivannan, Sathiyanarayanan, Majumdar, Uddalak, McBride, Kim L., White, Peter, Garg, Vidu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421733/
https://www.ncbi.nlm.nih.gov/pubmed/34504875
http://dx.doi.org/10.3389/fcvm.2021.683074