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Optimized Dosing Regimens of Meropenem in Septic Children Receiving Extracorporeal Life Support

Objectives: To develop a population pharmacokinetic model of meropenem in children with sepsis receiving extracorporeal life support (ECLS) and optimize the dosage regimen based on investigating the probability of target attainment (PTA). Methods: The children with sepsis were prospectively enrolled...

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Detalles Bibliográficos
Autores principales: Wang, Yixue, Chen, Weiming, Huang, Yidie, Wang, Guangfei, Li, Zhiping, Yan, Gangfeng, Chen, Chao, Lu, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421735/
https://www.ncbi.nlm.nih.gov/pubmed/34504424
http://dx.doi.org/10.3389/fphar.2021.699191