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Enhanced CXCR4 Expression of Human CD8(Low) T Lymphocytes Is Driven by S1P(4)

Although the human immune response to cancer is naturally potent, it can be severely disrupted as a result of an immunosuppressive tumor microenvironment. Infiltrating regulatory T lymphocytes contribute to this immunosuppression by inhibiting proliferation of cytotoxic CD8(+) T lymphocytes, which a...

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Detalles Bibliográficos
Autores principales: Burkard, Tobias, Dreis, Caroline, Herrero San Juan, Martina, Huhn, Meik, Weigert, Andreas, Pfeilschifter, Josef M., Radeke, Heinfried H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421764/
https://www.ncbi.nlm.nih.gov/pubmed/34504486
http://dx.doi.org/10.3389/fimmu.2021.668884