Identification of the Mouse T Cell ADP-Ribosylome Uncovers ARTC2.2 Mediated Regulation of CD73 by ADP-Ribosylation

Mouse T cells express the ecto-ADP-ribosyltransferase ARTC2.2, which can transfer the ADP-ribose group of extracellular nicotinamide adenine dinucleotide (NAD(+)) to arginine residues of various cell surface proteins thereby influencing their function. Several targets of ARTC2.2, such as P2X7, CD8a...

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Detalles Bibliográficos
Autores principales: Leutert, Mario, Duan, Yinghui, Winzer, Riekje, Menzel, Stephan, Tolosa, Eva, Magnus, Tim, Hottiger, Michael O., Koch-Nolte, Friedrich, Rissiek, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421852/
https://www.ncbi.nlm.nih.gov/pubmed/34504490
http://dx.doi.org/10.3389/fimmu.2021.703719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421852/
https://www.ncbi.nlm.nih.gov/pubmed/34504490
http://dx.doi.org/10.3389/fimmu.2021.703719

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