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Coarse-Grained Modeling and Molecular Dynamics Simulations of Ca(2+)-Calmodulin

Calmodulin (CaM) is a calcium-binding protein that transduces signals to downstream proteins through target binding upon calcium binding in a time-dependent manner. Understanding the target binding process that tunes CaM’s affinity for the calcium ions (Ca(2+)), or vice versa, may provide insight in...

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Detalles Bibliográficos
Autores principales: Nde, Jules, Zhang, Pengzhi, Ezerski, Jacob C., Lu, Wei, Knapp, Kaitlin, Wolynes, Peter G., Cheung, Margaret S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421859/
https://www.ncbi.nlm.nih.gov/pubmed/34504868
http://dx.doi.org/10.3389/fmolb.2021.661322