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Retinal degeneration in mice and humans with neuronal ceroid lipofuscinosis type 8

BACKGROUND: Ceroid lipofuscinosis type 8 belongs to a heterogenous group of vision and life-threatening neurodegenerative diseases, neuronal ceroid lipofuscinosis (NCL). Effective therapy is limited to a single drug for treatment of ceroid lipofuscinosis type 2, necessitating animal disease models t...

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Detalles Bibliográficos
Autores principales: Salpeter, Elyse M., Leonard, Brian C., Lopez, Antonio J., Murphy, Christopher J., Thomasy, Sara, Imai, Denise M., Grimsrud, Kristin, Lloyd, K. C. Kent, Yan, Jiong, Sanchez Russo, Rossana, Shankar, Suma P., Moshiri, Ala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421982/
https://www.ncbi.nlm.nih.gov/pubmed/34532411
http://dx.doi.org/10.21037/atm-20-4739