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Impairment of AMPK-α2 augments detrusor contractions in bladder ischemia

PURPOSE: Ischemia disrupts cellular energy homeostasis. Adenosine monophosphate-activated protein kinase alpha-2 (AMPK-α2) is a subunit of AMPK that senses cellular energy deprivation and signals metabolic stress. Our goal was to examine the expression levels and functional role of AMPK-α2 in bladde...

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Detalles Bibliográficos
Autores principales: Yang, Jing-Hua, Niu, Wanting, Li, Yedan, Azadzoi, Kazem M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Urological Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421994/
https://www.ncbi.nlm.nih.gov/pubmed/34387036
http://dx.doi.org/10.4111/icu.20210095