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Co-mutations of epidermal growth factor receptor and BRAF in Chinese non-small cell lung cancer patients

BACKGROUND: Epidermal growth factor receptor (EGFR) and BRAF are 2 driver genes in non-small cell lung cancer (NSCLC) which are normally mutually exclusive. It has been previously reported that the existence of BRAF V600E in EGFR-mutated NSCLC patients could cause resistance to EGFR tyrosine kinase...

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Detalles Bibliográficos
Autores principales: Peng, Panli, Lv, Guoli, Hu, Jinwei, Wang, Kai, Lv, Junhong, Guo, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422152/
https://www.ncbi.nlm.nih.gov/pubmed/34532458
http://dx.doi.org/10.21037/atm-21-3570