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A comparison of three mucus-secreting airway cell lines (Calu-3, SPOC1 and UNCN3T) for use as biopharmaceutical models of the nose and lung

The aim of this work was to compare three existing mucus-secreting airway cell lines for use as models of the airways to study drug transport in the presence of mucus. Each cell line secreted mature, glycosylated mucins, evidenced by the enzyme-linked lectin assay. The secretagogue, adenylyl-imidodi...

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Detalles Bibliográficos
Autores principales: Lee, Diane F., Lethem, Michael I., Lansley, Alison B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422164/
https://www.ncbi.nlm.nih.gov/pubmed/34332033
http://dx.doi.org/10.1016/j.ejpb.2021.07.016