Desymmetrization of Cyclic 1,3-Diketones under N-Heterocyclic Carbene Organocatalysis: Access to Organofluorines with Multiple Stereogenic Centers

Symmetric 1,3-diketones with fluorine or fluorinated substituents on the prochiral carbon remain to be established. Herein, we have developed a novel prochiral fluorinated oxindanyl 1,3-diketone and successfully applied these substrates in carbene-catalyzed asymmetric desymmetrization. Accordingly,...

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Detalles Bibliográficos
Autores principales: Wang, Guanjie, Zhang, Min, Guan, Yezhi, Zhang, Ye, Hong, Xianfang, Wei, Chenlong, Zheng, Pengcheng, Wei, Donghui, Fu, Zhenqian, Chi, Yonggui Robin, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422277/
https://www.ncbi.nlm.nih.gov/pubmed/34549186
http://dx.doi.org/10.34133/2021/9867915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422277/
https://www.ncbi.nlm.nih.gov/pubmed/34549186
http://dx.doi.org/10.34133/2021/9867915

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