Population pharmacokinetics and pharmacodynamics of investigational regimens’ drugs in the TB-PRACTECAL clinical trial (the PRACTECAL-PKPD study): a prospective nested study protocol in a randomised controlled trial

INTRODUCTION: Drug-resistant tuberculosis (TB) remains a global health threat, with little over 50% of patients successfully treated. Novel regimens like the ones being studied in the TB-PRACTECAL trial are urgently needed. Understanding anti-TB drug exposures could explain the success or failure of...

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Detalles Bibliográficos
Autores principales: Nyang'wa, Bern-Thomas, Kloprogge, Frank, Moore, David A.J., Bustinduy, Amaya, Motta, Ilaria, Berry, Catherine, Davies, Geraint R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Pharmacology and Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422304/
https://www.ncbi.nlm.nih.gov/pubmed/34489274
http://dx.doi.org/10.1136/bmjopen-2020-047185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422304/
https://www.ncbi.nlm.nih.gov/pubmed/34489274
http://dx.doi.org/10.1136/bmjopen-2020-047185

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