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Effect of melatonin and melatonin agonists on postoperative sleep quality in adult patients: a protocol for systematic review and meta-analysis with trial sequential analysis

INTRODUCTION: The circadian rhythm of melatonin secretion is disturbed after general anaesthesia, leading to postoperative sleep disturbance. Small studies investigating the preventive effect of melatonin administration on postoperative sleep disturbance have not reached any conclusions. Therefore,...

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Detalles Bibliográficos
Autores principales: Tsukinaga, Akito, Mihara, Takahiro, Takeshima, Teppei, Tomita, Makoto, Goto, Takahisa, Yamanaka, Takeharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422307/
https://www.ncbi.nlm.nih.gov/pubmed/34489275
http://dx.doi.org/10.1136/bmjopen-2020-047858