H3K36me3 and PSIP1/LEDGF associate with several DNA repair proteins, suggesting their role in efficient DNA repair at actively transcribing loci

Background: Trimethylation at histone H3 at lysine 36 (H3K36me3) is associated with expressed gene bodies and recruit proteins implicated in transcription, splicing and DNA repair. PC4 and SF2 interacting protein (PSIP1/LEDGF) is a transcriptional coactivator, possesses an H3K36me3 reader PWWP domai...

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Detalles Bibliográficos
Autores principales: Sundarraj, Jayakumar, Taylor, Gillian C.A., von Kriegsheim, Alex, Pradeepa, Madapura M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422350/
https://www.ncbi.nlm.nih.gov/pubmed/34541330
http://dx.doi.org/10.12688/wellcomeopenres.11589.4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422350/
https://www.ncbi.nlm.nih.gov/pubmed/34541330
http://dx.doi.org/10.12688/wellcomeopenres.11589.4

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