GDF15 induces immunosuppression via CD48 on regulatory T cells in hepatocellular carcinoma

BACKGROUND: A better understanding of the molecular mechanisms that manifest in the immunosuppressive tumor microenvironment (TME) is crucial for developing more efficacious immunotherapies for hepatocellular carcinoma (HCC), which has a poor response to current immunotherapies. Regulatory T (Treg)...

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Detalles Bibliográficos
Autores principales: Wang, Zhaowei, He, Lei, Li, Weina, Xu, Chuanyang, Zhang, Jieyu, Wang, Desheng, Dou, Kefeng, Zhuang, Ran, Jin, Boquan, Zhang, Wei, Hao, Qiang, Zhang, Kuo, Zhang, Wangqian, Wang, Shuning, Gao, Yuan, Gu, Jintao, Shang, Lei, Tan, Zhijun, Su, Haichuan, Zhang, Yingqi, Zhang, Cun, Li, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422483/
https://www.ncbi.nlm.nih.gov/pubmed/34489334
http://dx.doi.org/10.1136/jitc-2021-002787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422483/
https://www.ncbi.nlm.nih.gov/pubmed/34489334
http://dx.doi.org/10.1136/jitc-2021-002787

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