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SUPERGNOVA: local genetic correlation analysis reveals heterogeneous etiologic sharing of complex traits

Local genetic correlation quantifies the genetic similarity of complex traits in specific genomic regions. However, accurate estimation of local genetic correlation remains challenging, due to linkage disequilibrium in local genomic regions and sample overlap across studies. We introduce SUPERGNOVA,...

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Detalles Bibliográficos
Autores principales: Zhang, Yiliang, Lu, Qiongshi, Ye, Yixuan, Huang, Kunling, Liu, Wei, Wu, Yuchang, Zhong, Xiaoyuan, Li, Boyang, Yu, Zhaolong, Travers, Brittany G., Werling, Donna M., Li, James J., Zhao, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422619/
https://www.ncbi.nlm.nih.gov/pubmed/34493297
http://dx.doi.org/10.1186/s13059-021-02478-w