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SUPERGNOVA: local genetic correlation analysis reveals heterogeneous etiologic sharing of complex traits
Local genetic correlation quantifies the genetic similarity of complex traits in specific genomic regions. However, accurate estimation of local genetic correlation remains challenging, due to linkage disequilibrium in local genomic regions and sample overlap across studies. We introduce SUPERGNOVA,...
Autores principales: | Zhang, Yiliang, Lu, Qiongshi, Ye, Yixuan, Huang, Kunling, Liu, Wei, Wu, Yuchang, Zhong, Xiaoyuan, Li, Boyang, Yu, Zhaolong, Travers, Brittany G., Werling, Donna M., Li, James J., Zhao, Hongyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422619/ https://www.ncbi.nlm.nih.gov/pubmed/34493297 http://dx.doi.org/10.1186/s13059-021-02478-w |
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