Synergy of nanodiamond–doxorubicin conjugates and PD-L1 blockade effectively turns tumor-associated macrophages against tumor cells

BACKGROUND: Tumor-associated macrophages (TAMs) are the most abundant stromal cells in the tumor microenvironment. Turning the TAMs against their host tumor cells is an intriguing therapeutic strategy particularly attractive for patients with immunologically “cold” tumors. This concept was mechanist...

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Detalles Bibliográficos
Autores principales: Xu, Hua-Zhen, Li, Tong-Fei, Wang, Chao, Ma, Yan, Liu, Yan, Zheng, Mei-Yan, Liu, Zhang-Jun-Yan, Chen, Jin-Bo, Li, Ke, Sun, Shi-Kuan, Komatsu, Naoki, Xu, Yong-Hong, Zhao, Li, Chen, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422639/
https://www.ncbi.nlm.nih.gov/pubmed/34488792
http://dx.doi.org/10.1186/s12951-021-01017-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422639/
https://www.ncbi.nlm.nih.gov/pubmed/34488792
http://dx.doi.org/10.1186/s12951-021-01017-w

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