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Synergy of nanodiamond–doxorubicin conjugates and PD-L1 blockade effectively turns tumor-associated macrophages against tumor cells
BACKGROUND: Tumor-associated macrophages (TAMs) are the most abundant stromal cells in the tumor microenvironment. Turning the TAMs against their host tumor cells is an intriguing therapeutic strategy particularly attractive for patients with immunologically “cold” tumors. This concept was mechanist...
Autores principales: | Xu, Hua-Zhen, Li, Tong-Fei, Wang, Chao, Ma, Yan, Liu, Yan, Zheng, Mei-Yan, Liu, Zhang-Jun-Yan, Chen, Jin-Bo, Li, Ke, Sun, Shi-Kuan, Komatsu, Naoki, Xu, Yong-Hong, Zhao, Li, Chen, Xiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422639/ https://www.ncbi.nlm.nih.gov/pubmed/34488792 http://dx.doi.org/10.1186/s12951-021-01017-w |
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