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GDF11 expressed in the adult brain negatively regulates hippocampal neurogenesis
Growth differentiation factor 11 (GDF11) is a transforming factor-β superfamily member that functions as a negative regulator of neurogenesis during embryonic development. However, when recombinant GDF11 (rGDF11) is administered systemically in aged mice, it promotes neurogenesis, the opposite of it...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422669/ https://www.ncbi.nlm.nih.gov/pubmed/34488822 http://dx.doi.org/10.1186/s13041-021-00845-z |