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The Wnt signaling pathway in tumorigenesis, pharmacological targets, and drug development for cancer therapy
Wnt signaling was initially recognized to be vital for tissue development and homeostasis maintenance. Further studies revealed that this pathway is also important for tumorigenesis and progression. Abnormal expression of signaling components through gene mutation or epigenetic regulation is closely...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422786/ https://www.ncbi.nlm.nih.gov/pubmed/34488905 http://dx.doi.org/10.1186/s40364-021-00323-7 |