Transcriptional regulation of N(6)-methyladenosine orchestrates sex-dimorphic metabolic traits

Males and females exhibit striking differences in the prevalence of metabolic traits including hepatic steatosis, a key driver of cardiometabolic morbidity and mortality. RNA methylation is a widespread regulatory mechanism of transcript turnover. Here, we show that presence of the RNA modification...

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Detalles Bibliográficos
Autores principales: Salisbury, David A., Casero, David, Zhang, Zhengyi, Wang, Dan, Kim, Jason, Wu, Xiaohui, Vergnes, Laurent, Mirza, Aashiq H., Leon-Mimila, Paola, Williams, Kevin J., Huertas-Vazquez, Adriana, Jaffrey, Samie R., Reue, Karen, Chen, Jianjun, Sallam, Tamer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422857/
https://www.ncbi.nlm.nih.gov/pubmed/34282353
http://dx.doi.org/10.1038/s42255-021-00427-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422857/
https://www.ncbi.nlm.nih.gov/pubmed/34282353
http://dx.doi.org/10.1038/s42255-021-00427-2

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