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The fecal microbiome and rotavirus vaccine immunogenicity in rural Zimbabwean infants

BACKGROUND: Oral rotavirus vaccine (RVV) immunogenicity is considerably lower in low- versus high-income populations; however, the mechanisms underlying this remain unclear. Previous evidence suggests that the gut microbiota may contribute to differences in oral vaccine efficacy. METHODS: We perform...

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Detalles Bibliográficos
Autores principales: Robertson, Ruairi C., Church, James A., Edens, Thaddeus J., Mutasa, Kuda, Min Geum, Hyun, Baharmand, Iman, Gill, Sandeep K., Ntozini, Robert, Chasekwa, Bernard, Carr, Lynnea, Majo, Florence D., Kirkpatrick, Beth D., Lee, Benjamin, Moulton, Lawrence H., Humphrey, Jean H., Prendergast, Andrew J., Manges, Amee R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423000/
https://www.ncbi.nlm.nih.gov/pubmed/34393020
http://dx.doi.org/10.1016/j.vaccine.2021.07.076