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Pathology-specific experimental antivenoms for haemotoxic snakebite: The impact of immunogen diversity on the in vitro cross-reactivity and in vivo neutralisation of geographically diverse snake venoms

BACKGROUND: Snakebite is a neglected tropical disease that causes high global rates of mortality and morbidity. Although snakebite can cause a variety of pathologies in victims, haemotoxic effects are particularly common and are typically characterised by haemorrhage and/or venom-induced consumption...

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Detalles Bibliográficos
Autores principales: Alomran, Nessrin, Alsolaiss, Jaffer, Albulescu, Laura-Oana, Crittenden, Edouard, Harrison, Robert A., Ainsworth, Stuart, Casewell, Nicholas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423360/
https://www.ncbi.nlm.nih.gov/pubmed/34407084
http://dx.doi.org/10.1371/journal.pntd.0009659