Cargando…
Pathology-specific experimental antivenoms for haemotoxic snakebite: The impact of immunogen diversity on the in vitro cross-reactivity and in vivo neutralisation of geographically diverse snake venoms
BACKGROUND: Snakebite is a neglected tropical disease that causes high global rates of mortality and morbidity. Although snakebite can cause a variety of pathologies in victims, haemotoxic effects are particularly common and are typically characterised by haemorrhage and/or venom-induced consumption...
Autores principales: | Alomran, Nessrin, Alsolaiss, Jaffer, Albulescu, Laura-Oana, Crittenden, Edouard, Harrison, Robert A., Ainsworth, Stuart, Casewell, Nicholas R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423360/ https://www.ncbi.nlm.nih.gov/pubmed/34407084 http://dx.doi.org/10.1371/journal.pntd.0009659 |
Ejemplares similares
-
Correction: Pathology-specific experimental antivenoms for haemotoxic snakebite: The impact of immunogen diversity on the in vitro cross-reactivity and in vivo neutralisation of geographically diverse snake venoms
por: Alomran, Nessrin, et al.
Publicado: (2022) -
Exploring the Utility of Recombinant Snake Venom Serine Protease Toxins as Immunogens for Generating Experimental Snakebite Antivenoms
por: Alomran, Nessrin, et al.
Publicado: (2022) -
The paraspecific neutralisation of snake venom induced coagulopathy by antivenoms
por: Ainsworth, Stuart, et al.
Publicado: (2018) -
Exploring the Utility of ssDNA Aptamers Directed against Snake Venom Toxins as New Therapeutics for Snakebite Envenoming
por: Alomran, Nessrin, et al.
Publicado: (2022) -
Haemotoxic snake venoms: their functional activity, impact on snakebite victims and pharmaceutical promise
por: Slagboom, Julien, et al.
Publicado: (2017)