Brain gamma-aminobutyric acid, but not glutamine and glutamate levels are lower in older adults with chronic musculoskeletal pain: considerations by sex and brain location

INTRODUCTION AND OBJECTIVES: GABAergic and glutamatergic neurotransmitter systems are central to the pathophysiology of chronic pain and are equally affected by aging processes. We measured levels of frontal gamma-aminobutyric acid (GABA) and the combined resonance of glutamate and glutamine (Glx) i...

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Detalles Bibliográficos
Autores principales: Cruz-Almeida, Yenisel, Forbes, Megan, Cohen, Ronald C., Woods, Adam J., Fillingim, Roger B., Riley, Joseph L., Porges, Eric S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2021
Materias:
Musculoskeletal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423393/
https://www.ncbi.nlm.nih.gov/pubmed/34514275
http://dx.doi.org/10.1097/PR9.0000000000000952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423393/
https://www.ncbi.nlm.nih.gov/pubmed/34514275
http://dx.doi.org/10.1097/PR9.0000000000000952

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