Traumatic Brain Injury Induces cGAS Activation and Type I Interferon Signaling in Aged Mice

Aging adversely affects inflammatory processes in the brain, which has important implications in the progression of neurodegenerative disease. Following traumatic brain injury (TBI), aged animals exhibit worsened neurological function and exacerbated microglial-associated neuroinflammation. Type I I...

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Detalles Bibliográficos
Autores principales: Barrett, James P., Knoblach, Susan M., Bhattacharya, Surajit, Gordish-Dressman, Heather, Stoica, Bogdan A., Loane, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423402/
https://www.ncbi.nlm.nih.gov/pubmed/34504493
http://dx.doi.org/10.3389/fimmu.2021.710608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423402/
https://www.ncbi.nlm.nih.gov/pubmed/34504493
http://dx.doi.org/10.3389/fimmu.2021.710608

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