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β-hydroxybutyrate accumulates in the rat heart during low-flow ischaemia with implications for functional recovery

Extrahepatic tissues which oxidise ketone bodies also have the capacity to accumulate them under particular conditions. We hypothesised that acetyl-coenzyme A (acetyl-CoA) accumulation and altered redox status during low-flow ischaemia would support ketone body production in the heart. Combining a L...

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Detalles Bibliográficos
Autores principales: Lindsay, Ross T, Dieckmann, Sophie, Krzyzanska, Dominika, Manetta-Jones, Dominic, West, James A, Castro, Cecilia, Griffin, Julian L, Murray, Andrew J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423437/
https://www.ncbi.nlm.nih.gov/pubmed/34491199
http://dx.doi.org/10.7554/eLife.71270