Modeling human tumor-immune environments in vivo for the preclinical assessment of immunotherapies

Despite the significant contributions of immunocompetent mouse models to the development and assessment of cancer immunotherapies, they inadequately represent the genetic and biological complexity of corresponding human cancers. Immunocompromised mice reconstituted with a human immune system (HIS) a...

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Detalles Bibliográficos
Autores principales: Bareham, Bethany, Georgakopoulos, Nikitas, Matas-Céspedes, Alba, Curran, Michelle, Saeb-Parsy, Kourosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423639/
https://www.ncbi.nlm.nih.gov/pubmed/33830275
http://dx.doi.org/10.1007/s00262-021-02897-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423639/
https://www.ncbi.nlm.nih.gov/pubmed/33830275
http://dx.doi.org/10.1007/s00262-021-02897-5

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