ZBED6 counteracts high-fat diet-induced glucose intolerance by maintaining beta cell area and reducing excess mitochondrial activation

AIMS/HYPOTHESIS: ZBED6 (zinc finger, BED-type containing 6) is known to regulate muscle mass by suppression of Igf2 gene transcription. In insulin-producing cell lines, ZBED6 maintains proliferative capacity at the expense of differentiation and beta cell function. The aim was to study the impact of...

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Detalles Bibliográficos
Autores principales: Wang, Xuan, Younis, Shady, Cen, Jing, Wang, Yun, Krizhanovskii, Camilla, Andersson, Leif, Welsh, Nils
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423654/
https://www.ncbi.nlm.nih.gov/pubmed/34296320
http://dx.doi.org/10.1007/s00125-021-05517-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423654/
https://www.ncbi.nlm.nih.gov/pubmed/34296320
http://dx.doi.org/10.1007/s00125-021-05517-0

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