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The novel LSD1 inhibitor ZY0511 suppresses diffuse large B-cell lymphoma proliferation by inducing apoptosis and autophagy

Lysine-specific demethylase 1 (LSD1, also known as KDM1A) is an attractive agent for treatment of cancer. However, the anti-tumor effect of LSD1 inhibitors against diffuse large B-cell lymphoma (DLBCL) and the underlying mechanism are still unclear. Here, we report that KDM1A is overexpressed in hum...

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Detalles Bibliográficos
Autores principales: Liu, Huan, Wei, Jing, Sang, Na, Zhong, Xi, Zhou, Xia, Yang, Xinyu, Zhang, Jing, Zuo, Zeping, Zhou, Yang, Yang, Shengyong, Du, Junrong, Zhao, Yinglan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423655/
https://www.ncbi.nlm.nih.gov/pubmed/34491469
http://dx.doi.org/10.1007/s12032-021-01572-0