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DR15-DQ6 remains dominantly protective against type 1 diabetes throughout the first five decades of life

AIMS/HYPOTHESIS: Among white European children developing type 1 diabetes, the otherwise common HLA haplotype DR15-DQ6 is rare, and highly protective. Adult-onset type 1 diabetes is now known to represent more overall cases than childhood onset, but it is not known whether DR15-DQ6 is protective in...

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Detalles Bibliográficos
Autores principales: Thomas, Nicholas J., Dennis, John M., Sharp, Seth A., Kaur, Akaal, Misra, Shivani, Walkey, Helen C., Johnston, Desmond G., Oliver, Nick S., Hagopian, William A., Weedon, Michael N., Patel, Kashyap A., Oram, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423681/
https://www.ncbi.nlm.nih.gov/pubmed/34272580
http://dx.doi.org/10.1007/s00125-021-05513-4