HnRNP K mislocalisation is a novel protein pathology of frontotemporal lobar degeneration and ageing and leads to cryptic splicing

Heterogeneous nuclear ribonucleoproteins (HnRNPs) are a group of ubiquitously expressed RNA-binding proteins implicated in the regulation of all aspects of nucleic acid metabolism. HnRNP K is a member of this highly versatile hnRNP family. Pathological redistribution of hnRNP K to the cytoplasm has...

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Detalles Bibliográficos
Autores principales: Bampton, Alexander, Gatt, Ariana, Humphrey, Jack, Cappelli, Sara, Bhattacharya, Dipanjan, Foti, Sandrine, Brown, Anna-Leigh, Asi, Yasmine, Low, Yi Hua, Foiani, Marco, Raj, Towfique, Buratti, Emanuele, Fratta, Pietro, Lashley, Tammaryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423707/
https://www.ncbi.nlm.nih.gov/pubmed/34274995
http://dx.doi.org/10.1007/s00401-021-02340-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423707/
https://www.ncbi.nlm.nih.gov/pubmed/34274995
http://dx.doi.org/10.1007/s00401-021-02340-0

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