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Seizure-mediated iron accumulation and dysregulated iron metabolism after status epilepticus and in temporal lobe epilepsy

Neuronal dysfunction due to iron accumulation in conjunction with reactive oxygen species (ROS) could represent an important, yet underappreciated, component of the epileptogenic process. However, to date, alterations in iron metabolism in the epileptogenic brain have not been addressed in detail. I...

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Detalles Bibliográficos
Autores principales: Zimmer, Till S., David, Bastian, Broekaart, Diede W. M., Schidlowski, Martin, Ruffolo, Gabriele, Korotkov, Anatoly, van der Wel, Nicole N., van Rijen, Peter C., Mühlebner, Angelika, van Hecke, Wim, Baayen, Johannes C., Idema, Sander, François, Liesbeth, van Eyll, Jonathan, Dedeurwaerdere, Stefanie, Kessels, Helmut W., Surges, Rainer, Rüber, Theodor, Gorter, Jan A., Mills, James D., van Vliet, Erwin A., Aronica, Eleonora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423709/
https://www.ncbi.nlm.nih.gov/pubmed/34292399
http://dx.doi.org/10.1007/s00401-021-02348-6