Nitroalkene fatty acids modulate bile acid metabolism and lung function in obese asthma

Bile acid profiles are altered in obese individuals with asthma. Thus, we sought to better understand how obesity-related systemic changes contribute to lung pathophysiology. We also test the therapeutic potential of nitro-oleic acid (NO(2)-OA), a regulator of metabolic and inflammatory signaling pa...

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Detalles Bibliográficos
Autores principales: Manni, Michelle L., Heinrich, Victoria A., Buchan, Gregory J., O’Brien, James P., Uvalle, Crystal, Cechova, Veronika, Koudelka, Adolf, Ukani, Dharti, Rawas-Qalaji, Mohamad, Oury, Tim D., Hart, Renee, Ellgass, Madeline, Mullett, Steven J., Fajt, Merritt L., Wenzel, Sally E., Holguin, Fernando, Freeman, Bruce A., Wendell, Stacy G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423735/
https://www.ncbi.nlm.nih.gov/pubmed/34493738
http://dx.doi.org/10.1038/s41598-021-96471-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423735/
https://www.ncbi.nlm.nih.gov/pubmed/34493738
http://dx.doi.org/10.1038/s41598-021-96471-9

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