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Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding

The role of intestine clock in energy homeostasis remains elusive. Here we show that mice with Bmal1 specifically deleted in the intestine (Bmal1(iKO) mice) have a normal phenotype on a chow diet. However, on a high-fat diet (HFD), Bmal1(iKO) mice are protected against development of obesity and rel...

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Detalles Bibliográficos
Autores principales:	Yu, Fangjun, Wang, Zhigang, Zhang, Tianpeng, Chen, Xun, Xu, Haiman, Wang, Fei, Guo, Lianxia, Chen, Min, Liu, Kaisheng, Wu, Baojian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423749/ https://www.ncbi.nlm.nih.gov/pubmed/34493722 http://dx.doi.org/10.1038/s41467-021-25674-5

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