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Transcriptional network involving ERG and AR orchestrates Distal-less homeobox-1 mediated prostate cancer progression

Distal-less homeobox-1 (DLX1) is a well-established non-invasive biomarker for prostate cancer (PCa) diagnosis, however, its mechanistic underpinnings in disease pathobiology are not known. Here, we reveal the oncogenic role of DLX1 and show that abrogating its function leads to reduced tumorigenesi...

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Detalles Bibliográficos
Autores principales: Goel, Sakshi, Bhatia, Vipul, Kundu, Sushmita, Biswas, Tanay, Carskadon, Shannon, Gupta, Nilesh, Asim, Mohammad, Morrissey, Colm, Palanisamy, Nallasivam, Ateeq, Bushra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423767/
https://www.ncbi.nlm.nih.gov/pubmed/34493733
http://dx.doi.org/10.1038/s41467-021-25623-2