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Proximity proteomics identifies PAK4 as a component of Afadin–Nectin junctions

Human PAK4 is an ubiquitously expressed p21-activated kinase which acts downstream of Cdc42. Since PAK4 is enriched in cell-cell junctions, we probed the local protein environment around the kinase with a view to understanding its location and substrates. We report that U2OS cells expressing PAK4-Bi...

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Detalles Bibliográficos
Autores principales: Baskaran, Yohendran, Tay, Felicia Pei-Ling, Ng, Elsa Yuen Wai, Swa, Claire Lee Foon, Wee, Sheena, Gunaratne, Jayantha, Manser, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423818/
https://www.ncbi.nlm.nih.gov/pubmed/34493720
http://dx.doi.org/10.1038/s41467-021-25011-w