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Using multiple Mendelian randomization approaches and genetic correlations to understand obesity, urate, and gout
Observational studies suggest relationships between obesity, urate, and gout but are possibly confounded. We assessed whether genetically determined obesity, higher urate (and related traits), and gout were causal using multiple Mendelian randomization (MR) approaches and linkage disequilibrium scor...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423843/ https://www.ncbi.nlm.nih.gov/pubmed/34493793 http://dx.doi.org/10.1038/s41598-021-97410-4 |