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Using multiple Mendelian randomization approaches and genetic correlations to understand obesity, urate, and gout

Observational studies suggest relationships between obesity, urate, and gout but are possibly confounded. We assessed whether genetically determined obesity, higher urate (and related traits), and gout were causal using multiple Mendelian randomization (MR) approaches and linkage disequilibrium scor...

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Detalles Bibliográficos
Autores principales: Adams, Charleen D., Boutwell, Brian B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423843/
https://www.ncbi.nlm.nih.gov/pubmed/34493793
http://dx.doi.org/10.1038/s41598-021-97410-4