Growth Differentiation Factor-15 Produces Analgesia by Inhibiting Tetrodotoxin-Resistant Nav1.8 Sodium Channel Activity in Rat Primary Sensory Neurons

Growth differentiation factor 15 (GDF-15) is a member of the transforming growth factor-β superfamily. It is widely distributed in the central and peripheral nervous systems. Whether and how GDF-15 modulates nociceptive signaling remains unclear. Behaviorally, we found that peripheral GDF-15 signifi...

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Detalles Bibliográficos
Autores principales: Lin, Wei, Zhang, Wen-Wen, Lyu, Ning, Cao, Hong, Xu, Wen-Dong, Zhang, Yu-Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423960/
https://www.ncbi.nlm.nih.gov/pubmed/34076854
http://dx.doi.org/10.1007/s12264-021-00709-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423960/
https://www.ncbi.nlm.nih.gov/pubmed/34076854
http://dx.doi.org/10.1007/s12264-021-00709-5

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