Pre-clinical Investigation of Rett Syndrome Using Human Stem Cell-Based Disease Models

Rett syndrome (RTT) is an X-linked neurodevelopmental disorder, mostly caused by mutations in MECP2. The disorder mainly affects girls and it is associated with severe cognitive and physical disabilities. Modeling RTT in neural and glial cell cultures and brain organoids derived from patient- or mut...

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Detalles Bibliográficos
Autores principales: Haase, Florencia D., Coorey, Bronte, Riley, Lisa, Cantrill, Laurence C., Tam, Patrick P. L., Gold, Wendy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423999/
https://www.ncbi.nlm.nih.gov/pubmed/34512241
http://dx.doi.org/10.3389/fnins.2021.698812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423999/
https://www.ncbi.nlm.nih.gov/pubmed/34512241
http://dx.doi.org/10.3389/fnins.2021.698812

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