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Implications of FBXW7 in Neurodevelopment and Neurodegeneration: Molecular Mechanisms and Therapeutic Potential

The ubiquitin-proteasome system (UPS) mediated protein degradation is crucial to maintain quantitive and functional homeostasis of diverse proteins. Balanced cellular protein homeostasis controlled by UPS is fundamental to normal neurological functions while impairment of UPS can also lead to some n...

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Detalles Bibliográficos
Autores principales: Yang, Yu, Zhou, Xuan, Liu, Xinpeng, Song, Ruying, Gao, Yiming, Wang, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424092/
https://www.ncbi.nlm.nih.gov/pubmed/34512273
http://dx.doi.org/10.3389/fncel.2021.736008