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Population Pharmacokinetics of Polymyxin B and Dosage Optimization in Renal Transplant Patients
Currently, polymyxin B has been widely used in the treatment of multidrug-resistant Gram-negative pathogen infections. Due to the limited pharmacokinetic/pharmacodynamic data, the optimal dosage regimen for the recently proposed therapeutic target of the area under the concentration-time curve over...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424097/ https://www.ncbi.nlm.nih.gov/pubmed/34512352 http://dx.doi.org/10.3389/fphar.2021.727170 |