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Population Pharmacokinetics of Polymyxin B and Dosage Optimization in Renal Transplant Patients

Currently, polymyxin B has been widely used in the treatment of multidrug-resistant Gram-negative pathogen infections. Due to the limited pharmacokinetic/pharmacodynamic data, the optimal dosage regimen for the recently proposed therapeutic target of the area under the concentration-time curve over...

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Detalles Bibliográficos
Autores principales: Li, Ying, Deng, Yang, Zhu, Zhen-Yu, Liu, Yi-Ping, Xu, Ping, Li, Xin, Xie, Yue-Liang, Yao, Heng-Chang, Yang, Liu, Zhang, Bi-Kui, Zhou, Yan-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424097/
https://www.ncbi.nlm.nih.gov/pubmed/34512352
http://dx.doi.org/10.3389/fphar.2021.727170